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Treatment with SUN (25 mg/kg/day) for 28 successive days resulted in a significant 70% and 43% decrease in AMPK-2 level in serum and cardiac tissues, respectively, as compared to the control group

The authors found that placing pressure on these deformed cartilaginous tissues resulted in visible and sustained improvement in the shape of the auricular tissues

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Polar metabolites were extracted in 0.5 mL of cold 80% methanol containing internal standards (Cambridge Isotope Laboratories)